| Gene Symbol | GNAO1PROTEIN |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | - Plasma membrane (signal transduction) - Cytoplasm (protein synthesis) - Synapt |
| Molecular Weight | 40 kDa |
| GeneCards | GNAO1PROTEIN |
| Human Protein Atlas | GNAO1PROTEIN |
| Adenylate Cyclase Inhibition | Reduces cAMP production |
| Phospholipase C Modulation | Affects IP3/DAG signaling |
| Ion Channel Regulation | Modulates calcium and potassium channels |
| ERK/MAPK Pathways | Engages downstream kinase cascades |
| Cerebellum | Purkinje cells and granule cells |
| Basal Ganglia | Moderate expression |
| Brainstem | Moderate expression |
| EIEE15 | GNAO1 mutations cause EIEE15 |
| Seizure Types | Infantile spasms, myoclonic seizures |
| Associated Diseases | Als |
| KG Connections | 16 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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