protein 2,976 words KG: GSK3BETA 2026-03-24
kind:proteinsection:proteinsstate:published
Contents

GSK-3β

🔬 Protein Info
Gene SymbolGSK
Full Name3β (Glycogen Synthase Kinase 3 Beta)
AliasesGSK3BETA
FunctionGlycogen synthase kinase-3 beta (GSK-3β) is a serine/threonine kinase originally identified for its role in glycogen metabolism.
Subcellular LocalizationThe crystal structure of GSK-3β (PDB: 1H8F) reveals a bi-lobed kinase fold typical of eukaryotic protein kinases, with t
GeneCardsGSK
Human Protein AtlasGSK
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (30)

Multi-Target Hypothesis: Aβ-Induced Cholinergic Damage is Pa
Score: 0.70
Closed-loop focused ultrasound targeting EC-II SST interneur
Score: 0.70
Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.68
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
Vicious Cycle Hypothesis: Cholinergic Dysfunction Exacerbate
Score: 0.61

Related Analyses (11)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in