| Gene Symbol | HAP40 |
| Full Name | Huntingtin-Associated Protein 40 |
| Function | HAP40 interacts with huntingtin and has several cellular functions |
| Primary Expression | Brain (high), peripheral tissues |
| Subcellular Localization | Potential role in neuronal toxicity |
| Molecular Weight | 40 kDa |
| UniProt ID | Q9Y5R4 |
| GeneCards | HAP40 |
| Human Protein Atlas | HAP40 |
| HAP40 Expression | Altered in HD brain |
| Pathogenic Interaction | Enhanced binding to mutant HTT |
| Toxicity | May contribute to neuronal dysfunction |
| Therapeutic Target | Disrupt HAP40-HTT interaction |
| Biomarker Potential | HAP40 levels as disease marker |
| HAP40-HTT interaction inhibitors | Block pathogenic binding |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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