protein 2,541 words KG: HEMEOXYGENASE1PROTEIN
Contents

HEMEOXYGENASE1PROTEIN Protein

🔬 Protein Info
Gene SymbolHMOX1
Full NameHeme Oxygenase 1
Chromosome22q12
Protein TypeEnzyme
FunctionHMOX1 degrades heme to produce biliverdin (which is further converted to bilirubin), iron (which induces ferritin), and carbon monoxide (a signaling molecule).
Subcellular LocalizationEndoplasmic reticulum, mitochondria
Molecular Weight32 kDa
PathwaysAutophagy, Chaperone, Immune Response, Mitophagy, Oxidative Stress
UniProt IDP09601 (HO1_HUMAN)
NCBI Gene ID3162
Ensembl IDENSG00000101129
OMIM141250
GeneCardsHMOX1
Human Protein AtlasHMOX1
Protein NameHeme Oxygenase-1 (HO-1)
Associated DiseasesALS, Aging, Alzheimer, Atherosclerosis, Diabetes
Known Drugs/CompoundsL. reuteri-CMVs, rapamycin
InteractionsALOX15, ALOX12, NFE2L2, FER, CD4, ALOX5
KG Connections509 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph