protein 693 words KG: IL1BETAPROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

Interleukin-1 beta (IL-1β)

🔬 Protein Info
Gene SymbolIL1BETA
AliasesIL1BETAPROTEIN
Protein FamilyIL-1 family
FunctionInterleukin 1 Beta (Il 1Β) is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease pr...
Subcellular LocalizationCytosol, secreted
UniProt IDP01584
GeneCardsIL1BETA
Human Protein AtlasIL1BETA
GeneIL1B
PDB5R0J, 1S0L
Mol. Weight17.5 kDa (pro-IL-1β), 17 kDa (mature)
ReceptorsIL-1R1, IL-1R2
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (7)

SASP-Driven Aquaporin-4 Dysregulation
Score: 0.59
Context-Dependent Cx43 Modulation Based on Disease Stage
Score: 0.58
Metabolic Circuit Breaker via Lipid Droplet Modulation
Score: 0.48
Cardiovascular-Neuroinflammation Crosstalk Interruption
Score: 0.44
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51

Related Analyses (8)

Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (3)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Microglial Aging and Immune Memory in Neurodegeneration — Tr
validation · proposed · Score: 0.40
Neural Stem Cell Therapy for Alzheimer's Disease
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in