| Gene Symbol | JUP |
| Aliases | JUPPROTEIN |
| Chromosome | 17q21.1. |
| Function | JUP (junction plakoglobin), also known as gamma-catenin, is a member of the catenin protein family. It is a key component of desmosomes and adherens junctions, where it mediates cell-cell adhesion. |
| Molecular Weight | 81.7 kDa |
| Pathways | Wnt |
| GeneCards | JUP |
| Human Protein Atlas | JUP |
| β-Catenin (CTNNB1) | Functionally related armadillo family member with overlapping roles in adhesion and Wnt signaling |
| Desmosomal Cadherins | Direct binding partners including desmoglein and desmocollin |
| E-Cadherin (CDH1) | Major partner in adherens junction complexes |
| α-Catenin (CTNNA1) | Cytoskeletal linker protein in junctional complexes |
| Wnt Signaling Pathway | Key downstream effector of nuclear JUP function |
| GSK-3β | Major kinase regulating JUP phosphorylation and activity |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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