| Gene Symbol | KCNC3PROTEIN |
| Full Name | Kv3.3 |
| Protein Family | Voltage-gated potassium channels (Kv3 subfamily) |
| Protein Type | Channel |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | ~95 kDa |
| UniProt ID | Q9UK33 |
| GeneCards | KCNC3PROTEIN |
| Human Protein Atlas | KCNC3PROTEIN |
| 6 transmembrane segments (S1-S6) | S1-S4 form the voltage-sensing domain, while S5-S6 comprise the pore domain |
| Voltage sensor (S4) | Contains positively charged residues that respond to membrane depolarization |
| Pore region (S5-S6) | Forms the ion conduction pathway with high selectivity for K+ ions |
| Cytoplasmic N- and C-termini | Contain regulatory domains and binding sites for intracellular signaling molecules |
| Tetrameric assembly | Forms functional channels as tetramers of α subunits |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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