| Gene Symbol | KCND3PROTEIN |
| Protein Type | Channel |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | </th><td>Plasma Membrane (Dendrites)</td></tr> |
| Amino Acids | 4477 aa |
| GeneCards | KCND3PROTEIN |
| Human Protein Atlas | KCND3PROTEIN |
| S1-S6 segments | Six transmembrane α-helices |
| S4 voltage sensor | Positively charged residues detect membrane potential |
| P-loop (H5) | Forms the ion selectivity filter |
| S6 C-terminus | Forms the inner pore gate |
| N-terminal T1 domain | TetramERization domain, mediates auxiliary subunit interaction |
| KChIP binding site | Intracellular N-terminal binding for KChIP proteins |
| DPP6/DPP10 binding | C-terminal interaction for trafficking modulation |
| CaMKII phosphorylation | Enhances current, reduces inactivation |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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