protein 594 words KG: KCNH3PROTEIN
Contents

KCNH3 Protein — Neuronal Potassium Channel

🔬 Protein Info
Gene SymbolKCNH3
Full NamePotassium Voltage-Gated Channel Subfamily H Member 3
AliasesKCNH3PROTEIN
Protein TypeChannel
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionhippocampus and cortex
Subcellular Localization** | Plasma membrane |
UniProt IDQ9UQ98
Ensembl IDENSG00000135502
GeneCardsKCNH3
Human Protein AtlasKCNH3
N-terminusContains the PAS domain
S1-S4Voltage sensor domain
S5-S6Pore domain
C-terminusCyclic nucleotide-binding domain (CNBD)
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

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UniProtWikipedia

Related Hypotheses (8)

Programmable Neuronal Circuit Repair via Epigenetic CRISPR
Score: 0.63
Context-Dependent CRISPR Activation in Specific Neuronal Sub
Score: 0.68
Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lysosomal Calcium Channel Modulation Therapy
Score: 0.70
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.67
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (10)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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