| Gene Symbol | KIF1B |
| Full Name | Kinesin Family Member 1B |
| Aliases | KIF1BPROTEIN |
| Function | KIF1B encodes a motor protein of the kinesin-3 family that functions as a plus-end directed microtubule motor. |
| Subcellular Localization | </b></td><td>Cytoplasm, neuronal axons</td></tr> |
| Molecular Weight | 204 kDa |
| Ensembl ID | ENSG00000122952 |
| GeneCards | KIF1B |
| Human Protein Atlas | KIF1B |
| Motor Domain | N-terminal motor domain with ATPase activity that powers movement along microtubules |
| Coiled-coil Regions | Mediates dimerization and cargo binding |
| PH-like Domain | Forkhead-associated (FHA) domain for phosphothreonine recognition |
| C-terminal Tail | Regulates cargo binding and localization |
| Axonal Transport | Mediates anterograde transport of synaptic vesicles, mitochondria, and signaling complexes in neurons |
| Synaptic Function | Delivers presynaptic proteins to nerve terminals |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!