| Gene Symbol | KV33 |
| Protein Type | Channel |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | </th><td>Plasma membrane</td></tr> |
| Molecular Weight | 95 kDa |
| GeneCards | KV33 |
| Human Protein Atlas | KV33 |
| Voltage sensor domain | S1-S4 |
| Pore domain | S5-S6 |
| Voltage sensor | S4 helix with positively charged residues |
| Selective filter | KVFYF signature sequence |
| Activation voltage | Depolarized potentials (+10 to +50 mV) |
| Deactivation | Very fast (1-3 ms) |
| Current density | High in fast-spiking neurons |
| Modulation | Phosphorylation, oxidative stress |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!