| Gene Symbol | LC3C |
| Aliases | LC3CPROTEIN |
| Subcellular Localization | </th><td>Cytosol, Autophagosome membrane, Lysosome</td></tr> |
| Molecular Weight | 15 kDa |
| GeneCards | LC3C |
| Human Protein Atlas | LC3C |
| N-terminal region | Contains the ubiquitin-like fold domain that undergoes lipidation |
| C-terminal region | Contains the conserved glycine residue required for lipidation |
| Impaired autophagic-lysosomal pathway | Reduced LC3C lipidation and autophagosome formation leads to accumulation of amyloid-beta and tau aggregates |
| Defective mitophagy | Impaired clearance of damaged mitochondria contributes to neuronal energy deficits and oxidative stress |
| Synaptic dysfunction | Altered LC3C function affects synaptic protein turnover and plasticity [3] |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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