| Gene Symbol | LINGO1 |
| Chromosome | 19p13.3 |
| Protein Type | Protein |
| Function | is a transmembrane receptor protein that plays a critical role in the central nervous system (CNS) as a negative regulator of axonal regeneration, myelination, and synaptic plasticity. |
| Primary Expression | the CNS, where it coordinates signaling pathways that control neural development, oligodendrocyte function, and neuronal survival |
| Molecular Weight | 63 kDa |
| Amino Acids | 581 aa |
| UniProt ID | Search UniProt |
| GeneCards | LINGO1 |
| Human Protein Atlas | LINGO1 |
| Oligodendrocytes | Pre-myelinating and mature oligodendrocytes |
| Neurons | Particularly in cortical and hippocampal neurons |
| Astrocytes | Subpopulations of astrocytes in gray matter |
| Microglia | Low-level expression in activated microglia |
| Inhibits differentiation | Blocks the transition from OPC to mature oligodendrocyte |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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