protein 1,609 words KG: MEK2 2026-03-28
kind:proteinsection:proteinstopic:mapk-signalingtopic:neurodegenerationstate:published
Contents

MEK2 Protein

🔬 Protein Info
Gene SymbolMEK2
AliasesMAP2K2
Chromosome19p13.3
Protein FamilyMEK dual-specificity kinases
Protein TypeKinase
FunctionActive MEK2 then phosphorylates ERK1 (MAPK1/MAPK3) at specific threonine and tyrosine residues (T202/Y204 for ERK1, T185/Y187 for ERK2), enabling ERK to phosphorylate numerous downstream targets[@mapk
Molecular Weight44.2 kDa
Amino Acids400 aa
PathwaysMAPK, MAPK signaling
UniProt ID[P36507](https://www.uniprot.org/uniprot/P36507)
GeneCardsMEK2
Human Protein AtlasMEK2
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph