| Gene Symbol | MERLIN |
| Aliases | MERLINPROTEIN |
| Chromosome | 22q12.2. |
| Function | Merlin Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes. |
| Subcellular Localization | is tightly regulated
## Normal Function
Merlin functions as a scaffold protein |
| Molecular Weight | 70 kDa |
| Pathways | mTOR, mtor, MAPK, Notch signaling |
| GeneCards | MERLIN |
| Human Protein Atlas | MERLIN |
| Alpha-helical domain | Dimerization |
| C-terminal domain | Actin binding |
| Phosphorylation sites | Regulatory control |
| Hippo pathway | Activates YAP/TAZ inhibition |
| [mTOR](/entities/mtor) signaling | Inhibits mTORC1 |
| Ras-MAPK | Negatively regulates Ras signaling |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |