| Gene Symbol | MGLUR6 |
| Aliases | mGluR6/GRM6 |
| Chromosome | 5q33.1 |
| Protein Type | Receptor |
| Function | mGluR6 is a Group III metabotropic glutamate receptor expressed exclusively in retinal ON-bipolar cells. |
| Subcellular Localization | retinal ON-bipolar cells. This unique cellular distribution makes mGluR6 essential for scotopic (low-light) vision and t |
| Molecular Weight | 98 kDa |
| Exons | 9 |
| GeneCards | MGLUR6 |
| Human Protein Atlas | MGLUR6 |
| N-terminal VFT domain | Large extracellular domain (~400 aa) with ligand binding site |
| Cysteine-rich domain | Linker with structural disulfide bonds |
| 7 Transmembrane domain | Classic seven-helix bundle |
| C-terminal tail | Intracellular domain with unique features |
| Feature | ON-bipolar (mGluR6) |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |