| Gene Symbol | MGLUR7 |
| Aliases | mGluR7/GRM7 |
| Chromosome | 19p13.2 |
| Protein Type | Receptor |
| Function | mGluR7 is a Group III metabotropic glutamate receptor that acts as a presynaptic autoreceptor regulating glutamate release. |
| Subcellular Localization | and protein interactions. The GRM7 promoter contains regulatory elements for activity-dependent and tissue-specific expr |
| Molecular Weight | 103 kDa |
| Exons | 9 |
| GeneCards | MGLUR7 |
| Human Protein Atlas | MGLUR7 |
| N-terminal VFT domain | Large extracellular domain (~400 aa) with lowest glutamate affinity |
| Cysteine-rich domain | Linker with disulfide bonds |
| 7 Transmembrane domain | Classic seven-helix bundle |
| C-terminal tail | Long intracellular domain with multiple interaction motifs |
| Region | Expression Level |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |