protein 970 words KG: NERVEGROWTHFACTOR 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

Nerve Growth Factor (NGF)

🔬 Protein Info
Gene SymbolNGF
Full NameNerve Growth Factor
Chromosome1p13.1
Protein FamilyNeurotrophin family
Primary ExpressionPrimarily in nociceptive sensory neurons, cholinergic basal forebrain neurons, sympathetic ganglia
Subcellular LocalizationSecreted, extracellular
Molecular Weight~26 kDa (dimer)
Amino Acids120 aa
Exons3
PathwaysPI3K, MAPK
UniProt IDP01138
NCBI Gene ID4800
Ensembl IDENSG00000111665
OMIM162030
GeneCardsNGF
Human Protein AtlasNGF
Associated DiseasesALS, ANGIOGENESIS, Alzheimer, Alzheimer's disease, Amyotrophic Lateral Sclerosis
Known Drugs/Compoundsaducanumab, lecanemab, metformin
InteractionsCHR2, BDNF, GAIN, DCX, HES1, NESTIN
KG Connections799 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph