| Gene Symbol | NPY |
| Aliases | NEUROPEPTIDEYPROTEIN |
| Chromosome | 7p15.1 |
| Function | The NPY gene encodes a prepropeptide that undergoes proteolytic processing to yield the mature NPY peptide. |
| Primary Expression | hippocampus, Hypothalamus, Brainstem, Thalamus, Amygdala |
| Subcellular Localization | </strong> Secreted, dense-core vesicles</div> |
| Amino Acids | 36 aa |
| Pathways | Er Stress, Mtor, Lipid Metabolism, Autophagy, Akt |
| Ensembl ID | ENSG00000157240 |
| GeneCards | NPY |
| Human Protein Atlas | NPY |
| Proline residues | Confer rigidity and unique conformation |
| C-terminal tyrosine amide | Critical for receptor interaction |
| Hydrophobic core | Mediates peptide self-association |
| Receptor binding sites | Multiple regions interact with different receptors |
| Associated Diseases | ALS, Alzheimer, Alzheimer'S Disease, Asthma |
| Interactions | MTOR, NPY1R, GAIN, CRH, NGF, BDNF |
| KG Connections | 315 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |