| Gene Symbol | NIBRIN |
| Aliases | NIBRINPROTEIN |
| Function | Nibrin Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes. |
| Subcellular Localization | signals ### Post-Translational Modifications - **Phosphorylation**: Critical fo |
| Molecular Weight | 95 kDa |
| GeneCards | NIBRIN |
| Human Protein Atlas | NIBRIN |
| N-terminal Region | Contains ATM phosphorylation sites |
| Forkhead-Associated (FHA) Domain | Protein-protein interactions |
| BRCT Domain | DNA damage response interactions |
| C-terminal Region | Mediates interaction with MRE11 |
| Phosphorylation | Critical for DNA damage response |
| Complex Assembly | Essential for stable MRN complex formation |
| DNA Damage Recognition | Primary sensor of DSBs |
| Signal Amplification | Recruits and activates ATM kinase |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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