protein 1,154 words KG: OPALINPROTEIN
Contents

Opalin Protein

🔬 Protein Info
Gene SymbolOPALIN
Full NameOligodendrocyte Myelin Membrane Protein
AliasesGene profile for OPALIN
Chromosome10q22.2
Functionis a membrane protein specifically and highly expressed in oligodendrocytes and the myelin sheath within the central nervous system.
Primary Expressionoligodendrocytes and the myelin sheath within the central nervous system
Subcellular Localizationthe cytoplasmic leaflet of myelin
Molecular Weight60 kDa
Amino Acids30 aa
GeneCardsOPALIN
Human Protein AtlasOPALIN
N-terminal signal peptideDirects protein to the secretory pathway
Large extracellular domain1,500+ amino acids with extensive O-linked and N-linked glycosylation
Single transmembrane helixType I membrane protein topology
Short cytoplasmic tail~30 amino acids containing potential phosphorylation sites
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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