protein 561 words KG: PDE4APROTEIN 2026-03-17
kind:proteinsection:proteinsstate:published
Contents

PDE4A Protein — cAMP-Specific Phosphodiesterase 4A

🔬 Protein Info
Gene SymbolPDE4A
Full NamePhosphodiesterase 4A
AliasesPDE4APROTEIN
FunctionPDE4A encodes a cAMP-specific phosphodiesterase belonging to the PDE4 family
Subcellular Localization** | Cytosol, membrane |
UniProt IDP27815
Ensembl IDENSG00000065989
GeneCardsPDE4A
Human Protein AtlasPDE4A
N-terminal regionIsoform-specific, determines localization
Upstream conserved region (UCR)Regulatory domain
Catalytic domainC-terminal hydrolase domain
cAMP → AMPTermination of cAMP signaling
CompartmentalizationTargeted to specific cellular domains
Protein interactionsBinds to AKAPs, mTOR, ERK
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph