| Gene Symbol | PHOSPHOTAU |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| GeneCards | PHOSPHOTAU |
| Human Protein Atlas | PHOSPHOTAU |
| Epitope | Antibody |
| Ser202/Thr205 | AT8 |
| Thr231 | AT180 |
| Ser396/Ser404 | PHF-13 |
| Ser422 | pS422 |
| Marker | Clinical Utility |
| p-tau181 | Distinguishes AD from other dementias; correlates with NFT burden |
| [p-tau217](/biomarkers/p-tau-217) | Higher specificity for AD; detects earlier |
| p-tau231 | Early marker; tracks progression |
| Strategy | Approach |
| Kinase inhibitors | GSK-3β, CDK5 inhibitors |
| Associated Diseases | Alzheimer Disease, Alzheimer'S Disease, Neuronal loss, Tauopathy, aging, disease |
| Interactions | BETA-AMYLOID, ALZHEIMER, AMYLOID, AQP4, PHAGOCYTOSIS, APOE |
| KG Connections | 62 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |