| Gene Symbol | RIBOPHORINI |
| Aliases | RIBOPHORINIPROTEIN |
| Function | RPN1 is not itself the catalytic transferase (that role is carried by STT3A/STT3B-containing modules), but it is functionally required for efficient throughput and fidelity of cotranslational N-gly... |
| GeneCards | RIBOPHORINI |
| Human Protein Atlas | RIBOPHORINI |
| Pathway-level intervention | reducing ER proteotoxic load (rather than inhibiting RPN1) may preserve glycosylation fidelity.[@kelleher2006][@liu2024] |
| Systems biomarker role | combined signatures of OST/ER-stress transcripts may stratify patient subgroups with high secretory-pathway burden.[@wang2021][@profaci2022] |
| Combination logic | RPN1-linked biology could inform combination designs with modulators of ISR, autophagy, or glycoprotein trafficking.[@kelleher2006][@liu2024] |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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