| Gene Symbol | RPL23A |
| Aliases | RPL23APROTEIN |
| Chromosome | 17q21 |
| Function | RPL23A encodes a ribosomal protein that is a component of the 60S subunit. |
| Subcellular Localization | </strong></td><td>Cytoplasm (ribosome), Nucleus (extraribosomal)</td></tr> |
| Ensembl ID | ENSG00000156284 |
| GeneCards | RPL23A |
| Human Protein Atlas | RPL23A |
| Globular core domain | Forms the characteristic ribosomal protein architecture with a beta-barrel structure |
| Surface region | Contains binding sites for extraribosomal interactors including MDM2 |
| Peptidyl transferase activity | Contributes to the catalytic center that mediates peptide bond formation |
| rRNA interaction | Directly contacts 28S rRNA, stabilizing the large subunit structure |
| Ribosome assembly | Essential for proper 60S biogenesis; depletion impairs ribosomal subunit joining |
| Nascent chain interaction | Positioned near the exit tunnel to interact with newly synthesized polypeptides |
| Associated Diseases | neurodegeneration |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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