protein 558 words KG: SCN7APROTEIN
Contents

SCN7A Protein (Sodium Voltage-Gated Channel Alpha Subunit 7)

🔬 Protein Info
Gene SymbolSCN7A
Full NameSodium Voltage-Gated Channel Alpha Subunit 7
AliasesSCN7APROTEIN
Chromosome2q21.1
Protein TypeChannel
Functionencodes an atypical sodium channel that was originally designated as a "sodium leak channel" due to its unique gating properties, though subsequent research established its voltage-gated nature[@ei...
Primary Expressionsensory neurons, astrocytes, and certain hypothalamic nuclei, where it participates in sodium sensing, me
Molecular Weight220 kDa
Amino Acids018 aa
Exons24
UniProt IDQ9UQD0
NCBI Gene ID6332
Ensembl IDENSG00000136546
GeneCardsSCN7A
Human Protein AtlasSCN7A
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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Related Hypotheses (7)

Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lysosomal Calcium Channel Modulation Therapy
Score: 0.70
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.67
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.56

Related Analyses (11)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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