protein 574 words KG: SLC30A10PROTEIN
Contents

SLC30A10 Protein

🔬 Protein Info
Gene SymbolSLC30A10
Full NameSLC30A10 - Zinc Transporter 10
AliasesPage for SLC30A10
Chromosome10q25.1
Protein TypeGene
Functionis a member of the VPS10P domain receptor family that plays critical roles in neuronal survival, synaptic function, and intracellular trafficking.
Primary Expressionthe brain, with high levels in the hippocampus, cerebral cortex, and basal ganglia — regions cr
Molecular Weight50 kDa
Amino Acids460 aa
GeneCardsSLC30A10
Human Protein AtlasSLC30A10
Six transmembrane domainsForm the metal transport channel
N-terminal extracellular loopContains metal binding sites
C-terminal intracellular domainRegulates transport activity
HEXXH motifConserved metal binding sequence in transmembrane domain 5
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

UniProtWikipedia

Related Hypotheses (4)

SASP-Mediated Complement Cascade Amplification
Score: 0.82
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (7)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

Related Experiments (7)

Proposed experiment from debate on Synaptic pruning by micro
falsification · proposed · Score: 0.40
Proposed experiment from debate on Senolytics targeting p16/
falsification · proposed · Score: 0.40
Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?
clinical · proposed · Score: 0.40
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40
Mixed Pathology Effects on Parkinson's Disease Progression a
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.