| Gene Symbol | SLIT1PROTEIN |
| Full Name | Slit homolog 1 protein |
| Protein Family | Slit family (SLIT1-3) |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | the midline raphe and acts as a chemorepulsive cue for commissural axons: |
| Subcellular Localization | </td><td>Extracellular matrix, growth cones, plasma membrane</td></tr> |
| Molecular Weight | ~170 kDa (full-length); ~140 kDa (processed) |
| UniProt ID | Q9MQZ3 |
| GeneCards | SLIT1PROTEIN |
| Human Protein Atlas | SLIT1PROTEIN |
| Midline avoidance | Slit1-Robo signaling prevents axons from crossing the midline, ensuring proper formation of bilateral neural circuits |
| Corticospinal tract | Slit1 guides corticospinal motor neurons to their correct targets |
| Olfactory system | Slit1 mediates the organization of olfactory bulb interneurons |
| Cortical interneurons | Guides GABAergic interneurons from the medial ganglionic eminence to the cortex |
| GnRH neurons | Influences the migration of gonadotropin-releasing hormone neurons |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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