| Gene Symbol | SPECTRINALPHA |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | various tissues including the brain and plays roles in neuronal function and disease mechanisms |
| Molecular Weight | 284 kDa |
| GeneCards | SPECTRINALPHA |
| Human Protein Atlas | SPECTRINALPHA |
| SPTAN1 gene | Encodes the non-erythrocytic spectrin alpha chain |
| Spectrin beta protein | Forms heterodimers with spectrin alpha |
| Ankyrin | Major binding partner organizing spectrin complexes |
| Calpain proteases | Mediate spectrin alpha proteolysis in neurodegeneration |
| Axon initial segment | Critical neuronal compartment requiring spectrin alpha |
| Alpha-synuclein | Interacts pathologically with spectrin in Parkinson's disease |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |