| Gene Symbol | SYNDECAN3 |
| Function | In the healthy brain, Syndecan-3 has several important functions |
| Primary Expression | hypothalamus, regulates energy homeostasis 5 |
| Molecular Weight | ~44 kDa (core) |
| UniProt ID | [Q99971](https://www.uniprot.org/uniprotkb/Q99971) |
| GeneCards | SYNDECAN3 |
| Human Protein Atlas | SYNDECAN3 |
| Ectodomain | Contains heparan sulfate (HS) and chondroitin sulfate (CS) glycosaminoglycan (GAG) attachment sites |
| Transmembrane domain | Single-pass membrane anchor highly conserved among syndecans |
| Cytoplasmic domain | Contains variable (V) region, conserved (C1 and C2) regions, and binds intracellular signaling proteins |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsNCBI GeneHPASTRING |
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