protein 936 words KG: SYNJ2PROTEIN
Contents

Synaptojanin 2 Protein

🔬 Protein Info
Gene SymbolSYNJ2PROTEIN
Protein TypePhosphatase
Functionis an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localization- **SYNJ2b**: Broader expression including immune cells and cancer cells ## Mol
Molecular Weight175 kDa
GeneCardsSYNJ2PROTEIN
Human Protein AtlasSYNJ2PROTEIN
C2 domainsCalcium-dependent membrane association
SYNJ2aNeuron-specific isoform with presynaptic localization
SYNJ2bBroader expression including immune cells and cancer cells
AMPA Receptor EndocytosisControls synaptic strength through receptor trafficking
Dendritic Spine MorphogenesisRegulates spine development and maintenance
Long-term Depression (LTD)Mediates activity-dependent synaptic weakening
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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