protein 1,206 words KG: VESICULARGABATRANSPORTER 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

Vesicular GABA Transporter

🔬 Protein Info
Gene SymbolVESICULARGABATRANSPORTER
AliasesVESICULARGABATRANSPORTER
Subcellular Localizationthe membrane of synaptic vesicles in GABAergic and glycinergic neurons. The transporter is densely
Transmembrane Domains12 alpha-helical transmembrane segments that span the synaptic vesicle membrane
Substrate Binding SiteA central cavity that recognizes and binds GABA and glycine with high specificity
Proton Coupling DomainConserved residues that facilitate proton-coupled transport
N- and C-terminal Cytoplasmic DomainsRegulatory regions that interact with vesicular proteins and trafficking machinery
CerebellumPurkinje cells and molecular layer interneurons
BrainstemReticular formation and cranial nerve nuclei
Spinal CordDorsal horn inhibitory interneurons
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph