| Gene Symbol | XRCC7 |
| Full Name | X-Ray Repair Cross-Complementing 7 / DNA-PK Catalytic Subunit |
| Aliases | DNA-PKcs |
| Chromosome | 8q24.21 |
| Protein Family | PI3/PI4-related protein kinases |
| Function | is a central component of the non-homologous end joining (NHEJ) pathway, the predominant mechanism for repairing DNA double-strand breaks (DSBs) in mammalian cells. |
| Primary Expression | virtually all cell types: |
| Molecular Weight | ~469 kDa |
| Amino Acids | 4128 aa |
| UniProt ID | P78527 |
| NCBI Gene ID | 5591 |
| Ensembl ID | ENSG00000137413 |
| OMIM | 604743 |
| GeneCards | XRCC7 |
| Human Protein Atlas | XRCC7 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsHPASTRING |