| Gene Symbol | ZFYVE26 |
| Aliases | SPG15 |
| Chromosome | 14q24.3 |
| Function | is a gene encoding a critical autophagy protein that plays essential roles in cellular protein homeostasis and organelle quality control. |
| Molecular Weight | 235 kDa |
| Amino Acids | 100 aa |
| GeneCards | ZFYVE26 |
| Human Protein Atlas | ZFYVE26 |
| N-terminal FYVE domain | Phosphatidylinositol 3-phosphate (PI3P) binding motif that targets the protein to endosomal and autophagosomal membranes |
| Multiple C2H2 zinc finger domains | Six zinc finger motifs involved in protein-protein interactions and DNA binding |
| Coiled-coil regions | Facilitate dimerization and oligomerization |
| Proline-rich regions | Potential SH3 domain binding sites |
| C-terminal region | Contains additional protein interaction domains |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!