gene 813 words KG: SEPTIN4
Contents

Septin 4

🧬 Gene Info
Gene SymbolSEPTIN4
Full NameSeptin 4
Chromosome17q23.1
Functionis an important component in the neurobiology of neurodegenerative diseases.
Subcellular LocalizationSEPTIN4 exhibits distinctive subcellular distribution:
Molecular Weight43 kDa
PathwaysTGF-β signaling, TGF-β Signaling, TGF-β
UniProt IDO43291
GeneCardsSEPTIN4
Human Protein AtlasSEPTIN4
Hetero-oligomeric complexesSEPTIN4 assembles with other septins (SEPT1, SEPT2, SEPT3, SEPT5, SEPT6, SEPT7, SEPT8, SEPT9, SEPT10, SEPT11, SEPT12, SEPT14) into complexes
Filaments and bundlesThese complexes can polymerize into filaments and higher-order bundles
Membrane associationSEPTIN4 localizes to membrane compartments, particularly Golgi and plasma membrane
ParkinInteractions with E3 ubiquitin ligase parkin
TubulinSEPTIN4 can associate with microtubules
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

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