protein 699 words KG: HTR2BPROTEIN
Contents

Serotonin Receptor 2B Protein

🔬 Protein Info
Gene SymbolHTR2BPROTEIN
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionthe prefrontal cortex, hippocampus, and basal ganglia
Subcellular Localization</th><td>Plasma Membrane</td></tr>
Amino Acids4477 aa
GeneCardsHTR2BPROTEIN
Human Protein AtlasHTR2BPROTEIN
Basal GangliaModerate expression in striatum and substantia nigra
AmygdalaSpecific expression in basolateral and central nuclei
ThalamusLimited expression in midline nuclei
BrainstemExpression in dorsal raphe nucleus and serotonin cell bodies
AgonistsPotential for mood and cognitive enhancement
AntagonistsMay provide neuroprotection in specific contexts
biased LigandsTarget specific signaling pathways to maximize therapeutic benefit
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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