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disease 3,723 words KG: ent-dise-d5f19751
Contents

Variably Protease-Sensitive Prionopathy (VPSPr)

Disease Info
129MMMajority of VPSPr cases
129VVMinority of VPSPr cases
129MVRare in VPSPr (contrast with sCJD)
Gene locationChromosome 20p13
DatabasesOMIMOrphanetClinicalTrialsPubMed

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🌐 Cross-references

OMIMMeSHWikipedia

Related Hypotheses (6)

Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
Score: 0.65TREM2-mediated microglial tau clearance enhancement
Score: 0.62LRP1-Dependent Tau Uptake Disruption
Score: 0.60Brain Insulin Resistance with Glucose Transporter Dysfunctio
Score: 0.60

Related Analyses (3)

SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completedTau propagation mechanisms and therapeutic interception poin
neurodegeneration · archivedMetabolic reprogramming in neurodegenerative disease
neurodegeneration · completed

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