Scientific World Model

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

Showing 1–50 of 100 pages matching "FTD"

⚙️ Frontotemporal Dementia (FTD) Mechanistic PathwayKG

mechanism · 5,506 words · 37 hyp43 ana17 exp

🏥 Frontotemporal Dementia (FTD)KG

disease · 5,230 words · 52 hyp17 ana21 exp

⚙️ ftd-tdp-pathologyKG

mechanism · 4,657 words · 11 hyp54 ana25 exp

⚙️ Epigenetic Dysregulation Comparison -- AD/PD/ALS/FTD/HDKG

mechanism · 4,361 words · 54 hyp46 ana46 exp

⚙️ Lipid Metabolism Dysfunction Comparison — AD/PD/ALS/FTD/HDKG

mechanism · 3,831 words · 45 hyp41 ana46 exp

⚙️ Autophagy-Lysosomal Impairment Comparison — AD/PD/ALS/FTD/HDKG

mechanism · 3,688 words · 38 hyp37 ana45 exp

⚙️ Neuroinflammation Across AD, PD, ALS, FTD, and HDKG

mechanism · 3,668 words · 54 hyp54 ana47 exp

🏥 ALS-FTD SpectrumKG

disease · 3,586 words · 20 hyp22 ana63 exp

⚙️ Tau Pathology Pathway in Frontotemporal DementiaKG

mechanism · 3,486 words · 28 hyp47 ana8 exp

⚙️ Autophagy Failure Comparison -- AD/PD/ALS/FTD/HDKG

mechanism · 3,424 words · 18 hyp39 ana37 exp

⚙️ TREM2 in Frontotemporal DementiaKG

mechanism · 3,364 words · 46 hyp55 ana42 exp

⚙️ Ion Channel Dysfunction in Frontotemporal DementiaKG

mechanism · 3,283 words · 23 hyp43 ana4 exp

⚙️ ftd-tdp43-pathwayKG

mechanism · 3,217 words · 37 hyp46 ana29 exp

⚙️ FTD Tau Subtypes Comparison: 3R vs 4R TauopathiesKG

mechanism · 3,179 words · 6 hyp38 ana23 exp

🏥 FTD-ALS SpectrumKG

disease · 3,096 words · 33 hyp25 ana60 exp

⚙️ C9orf72→RNA/Dipeptide Repeat Pathology→ALS/FTD — Causal ChainKG

mechanism · 3,056 words · 22 hyp60 ana47 exp

🧫 Mechanism: Progranulin Loss and TDP-43 Pathology in FTDKG

experiment · 2,916 words · 20 hyp17 ana14 exp

⚙️ Neuroinflammation Comparison — AD/PD/ALS/FTD/HDKG

mechanism · 2,902 words · 36 hyp39 ana48 exp

⚙️ Neuroimmune Dysfunction in Frontotemporal DementiaKG

mechanism · 2,778 words · 65 hyp44 ana32 exp

⚙️ FUS Gene-Mechanism-Therapy Causal Chain — ALS/FTDKG

mechanism · 2,751 words · 54 hyp62 ana30 exp

⚙️ GRN Progranulin FTD Causal ChainKG

mechanism · 2,744 words · 32 hyp42 ana25 exp

⚙️ Neurovascular Coupling Disease Comparison — AD/PD/ALS/FTD/HDKG

mechanism · 2,700 words · 27 hyp46 ana31 exp

⚙️ Mitochondrial Dysfunction in ALS-FTD SpectrumKG

mechanism · 2,636 words · 51 hyp59 ana29 exp

⚙️ VCP→TDP-43→ALS/FTD Causal ChainKG

mechanism · 2,601 words · 11 hyp55 ana37 exp

⚙️ Semantic Variant PPA: Mechanisms of Language Network DegenerationKG

mechanism · 2,586 words · 26 hyp54 ana3 exp

⚙️ AD-FTD Tau-TDP-43 Overlap: Mechanism ComparisonKG

mechanism · 2,557 words · 28 hyp50 ana22 exp

⚙️ Behavioral Variant FTD: Network and Molecular MechanismsKG

mechanism · 2,512 words · 10 hyp39 ana10 exp

⚙️ Interoceptive Brain Dynamics in bvFTDKG

mechanism · 2,488 words · 26 hyp39 ana10 exp

🏥 ALS-FTD-Parkinsonism Comparison MatrixKG

disease · 2,452 words · 43 hyp27 ana66 exp

⚙️ OPTN (Optineurin) Mitophagy Dysfunction — ALS/FTD/PD Causal ChainKG

mechanism · 2,356 words · 150 hyp58 ana39 exp

⚙️ PTPσ (PTPRS) in C9ORF72-ALS/FTD - PI3P Regulation MechanismKG

mechanism · 2,248 words · 20 hyp49 ana25 exp

🧫 FTD Microglia Role: Protective vs Destructive Mechanism StudyKG

experiment · 2,110 words · 17 hyp20 ana26 exp

⚙️ TREM2 in FTDKG

mechanism · 2,101 words · 61 hyp59 ana48 exp

⚙️ C9orf72 Hexanucleotide Repeat Expansion Pathway in ALS and FTDKG

mechanism · 2,088 words · 25 hyp53 ana37 exp

TBK1-Mediated Neuroinflammation Hypothesis — Autophagy Failure and Innate Immune Dysregulation in FTD/ALSKG

hypothesis · 2,087 words · 49 hyp51 ana40 exp

⚙️ Myelin Pathology Disease Comparison — AD/PD/ALS/FTD/HDKG

mechanism · 1,971 words · 21 hyp45 ana28 exp

⚙️ Progranulin Haploinsufficiency in Frontotemporal DementiaKG

mechanism · 1,947 words · 18 hyp41 ana7 exp

⚙️ Oligodendrocyte Dysfunction: AD vs PD vs ALS vs FTD vs HD ComparisonKG

mechanism · 1,883 words · 15 hyp46 ana29 exp

⚙️ Microglia in Frontotemporal Dementia ProgressionKG

mechanism · 1,832 words · 192 hyp78 ana17 exp

🏥 Behavioral Variant Frontotemporal Dementia (bvFTD)KG

disease · 1,782 words · 16 hyp12 ana16 exp

⚙️ ALS-FTD Overlap: Mechanistic PathwaysKG

mechanism · 1,772 words · 21 hyp53 ana66 exp

⚙️ PGC-1α Mitochondrial Biogenesis Comparison — AD/PD/ALS/FTD/HDKG

mechanism · 1,731 words · 49 hyp42 ana48 exp

⚙️ Microglia Dysfunction: AD vs PD vs ALS vs FTD vs HD ComparisonKG

mechanism · 1,623 words · 55 hyp57 ana42 exp

🏥 FTD Subtype Comparison Matrix — bvFTD vs svPPA vs nfPPA vs logopenicKG

disease · 1,622 words · 6 hyp12 ana24 exp

💊 Antisense Oligonucleotide Therapy for C9orf72 ALS/FTDKG

therapeutic · 1,606 words · 22 hyp35 ana38 exp

⚙️ CBS-FTD Overlap SyndromeKG

mechanism · 1,566 words · 4 hyp36 ana20 exp

Frontotemporal Dementia (FTD) BiomarkersKG

diagnostic · 1,542 words · 3 hyp9 ana10 exp

⚙️ Ferroptosis Disease Comparison — AD/PD/ALS/FTD/HDKG

mechanism · 1,521 words · 11 hyp42 ana32 exp

🏥 AD-PD-FTD Comparison MatrixKG

disease · 1,511 words · 18 hyp7 ana12 exp

⚙️ FUS Proteinopathy in Frontotemporal DementiaKG

mechanism · 1,505 words · 12 hyp42 ana4 exp