mechanism 3,056 words KG: ent-dise-93f3d65f 2026-03-31
kind:mechanismsection:mechanismsstate:publishedevidence:strong
Contents

C9orf72→RNA/Dipeptide Repeat Pathology→ALS/FTD — Causal Chain

Mechanism Info
NameC9orf72→RNA/Dipeptide Repeat Pathology→ALS/FTD — Causal Chain
SummaryComplete causal chain tracing C9orf72 hexanucleotide repeat expansion through RNA foci formation, dipeptide repeat proteins, and nucleocytoplasmic transport defects to amyotrophic lateral sclerosis and frontotemporal dementia

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Related Hypotheses (22)

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Related Analyses (30)

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Related Experiments (30)

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