Scientific World Model

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

Showing 1–50 of 110 pages matching "microglia"

⚙️ Microglia CD8+ T Cell Recruitment -- Supplementary WW ContentKG

mechanism · 7,227 words · 55 hyp47 ana13 exp

🔬 Microglial Cells — Cell Type HierarchyKG

cell · 5,150 words · 51 hyp14 ana17 exp

⚙️ TREM2 Microglial Signaling Pathway in NeurodegenerationKG

mechanism · 4,613 words · 329 hyp74 ana95 exp

⚙️ Microglial Senescence Pathway in NeurodegenerationKG

mechanism · 3,902 words · 302 hyp55 ana61 exp

⚙️ TREM2→Microglial Dysfunction→Alzheimer's Disease Causal ChainKG

mechanism · 3,665 words · 93 hyp66 ana90 exp

Neuroinflammation MicrogliaKG

cell_type · 3,294 words · 36 hyp21 ana23 exp

⚙️ microglial-synaptic-pruning-dysregulationKG

mechanism · 3,254 words · 70 hyp48 ana8 exp

⚙️ Microglial Phagocytosis in NeurodegenerationKG

mechanism · 3,212 words · 306 hyp59 ana59 exp

⚙️ Microglia Activation MechanismKG

mechanism · 3,164 words · 204 hyp72 ana32 exp

⚙️ TLR5-Mediated Microglial Neuroinflammation HypothesisKG

mechanism · 3,154 words · 44 hyp49 ana11 exp

⚙️ Neuroinflammation and Microglia PathwayKG

mechanism · 2,949 words · 71 hyp51 ana22 exp

nlrp3-inflammasome-activated-microgliaKG

cell_type · 2,939 words · 171 hyp19 ana18 exp

🔬 MicrogliaKG

cell · 2,899 words · 288 hyp107 ana109 exp

⚙️ CBS Microglial Neuroimmune AxisKG

mechanism · 2,847 words · 55 hyp41 ana21 exp

⚙️ Microglia and neuroinflammation in Alzheimer's DiseaseKG

mechanism · 2,789 words · 206 hyp79 ana76 exp

⚙️ TYROBP/DAP12 Microglia Signaling Pathway in Alzheimer's DiseaseKG

mechanism · 2,768 words · 109 hyp59 ana57 exp

⚙️ Microglia-Neuron Metabolic Cross-Talk in NeurodegenerationKG

mechanism · 2,668 words · 347 hyp74 ana78 exp

📊 Microglial Proteins in CSF Reveal AD Progression StatesKG

biomarker · 2,643 words · 33 hyp18 ana3 exp

💡 Microglia-State Editing via TREM2-LXR Pulse ProgramKG

idea · 2,572 words · 200 hyp83 ana20 exp

⚙️ SYK Kinase in Microglial Activation and Alzheimer's DiseaseKG

mechanism · 2,557 words · 71 hyp56 ana57 exp

⚙️ Microglial State Trajectory from Mobilization to Dysregulation in Alzheimer's DiseaseKG

mechanism · 2,523 words · 103 hyp54 ana65 exp

💡 Microglia-Targeted Nanoparticles for CNS DeliveryKG

idea · 2,474 words · 177 hyp67 ana23 exp

💡 GPNMB Modulation for Lipid-Laden Microglia RescueKG

idea · 2,450 words · 52 hyp33 ana24 exp

🔬 iPSC-Derived MicrogliaKG

cell · 2,432 words · 100 hyp55 ana15 exp

💡 Engineered iPSC-Microglia Cell Therapy for NeurodegenerationKG

idea · 2,401 words · 294 hyp51 ana62 exp

⚙️ SYK Kinase in Microglial Activation and Alzheimer's DiseaseKG

mechanism · 2,366 words · 76 hyp57 ana56 exp

💡 Microglia-State Editing via TREM2-LXR Pulse ProgramKG

idea · 2,293 words · 200 hyp83 ana22 exp

⚙️ TREM2 Microglia Pathway in Alzheimer's DiseaseKG

mechanism · 2,264 words · 99 hyp75 ana87 exp

⚙️ Microglial PolarizationKG

mechanism · 2,187 words · 58 hyp47 ana16 exp

💡 CSF1R-Targeted Microglia TherapyKG

idea · 2,114 words · 37 hyp31 ana6 exp

🧫 FTD Microglia Role: Protective vs Destructive Mechanism StudyKG

experiment · 2,110 words · 17 hyp20 ana26 exp

⚙️ Microglial Dysfunction in Alzheimer's DiseaseKG

mechanism · 2,063 words · 77 hyp54 ana58 exp

🔬 Neuroprotective MicrogliaKG

cell · 2,031 words · 33 hyp26 ana10 exp

⚙️ CR3-Dependent Microglial Synapse Elimination in Parkinson's DiseaseKG

mechanism · 1,931 words · 46 hyp51 ana64 exp

💡 sTREM2-Modulated Microglial TherapyKG

idea · 1,880 words · 48 hyp24 ana8 exp

💡 CSF1R Modulation Therapy: Microglia Reset ProtocolKG

idea · 1,879 words · 52 hyp34 ana6 exp

⚙️ Microglia in Frontotemporal Dementia ProgressionKG

mechanism · 1,832 words · 192 hyp78 ana17 exp

⚙️ PLCG2 Microglial Signaling Phagocytosis AD Causal ChainKG

mechanism · 1,757 words · 62 hyp37 ana3 exp

🔬 Nigral Microglia in Progressive Supranuclear PalsyKG

cell · 1,726 words · 15 hyp21 ana33 exp

🏢 AD Microglial Phagocytosis and Synaptic Pruning CompaniesKG

company · 1,725 words · 21 hyp13 ana

⚙️ Microglia CD8+ T Cell Recruitment in White Matter DegenerationKG

mechanism · 1,623 words · 44 hyp45 ana6 exp

⚙️ Microglia Dysfunction: AD vs PD vs ALS vs FTD vs HD ComparisonKG

mechanism · 1,623 words · 55 hyp57 ana42 exp

🔬 Primed MicrogliaKG

cell · 1,613 words · 32 hyp21 ana10 exp

Microglia Modulation TherapiesKG

therapeutics · 1,608 words · 181 hyp68 ana17 exp

⚙️ Microglia in Corticobasal DegenerationKG

mechanism · 1,549 words · 191 hyp72 ana17 exp

⚙️ Disease-Associated [Microglia](/cell-types/microglia-neuroinflammation) (DAM)KG

mechanism · 1,535 words · 48 hyp51 ana15 exp

⚙️ Microglial Priming Pathway in NeurodegenerationKG

mechanism · 1,528 words · 305 hyp55 ana62 exp

🔬 Microglia in Batten DiseaseKG

cell · 1,440 words · 186 hyp74 ana16 exp

⚙️ Microglial Metabolic ReprogrammingKG

mechanism · 1,360 words · 60 hyp48 ana12 exp

Microglia Depletion and Repopulation TherapyKG

treatment · 1,355 words · 177 hyp68 ana14 exp