🔬
How does SYNGAP1, a 'synaptic' protein, function in pre-synaptic radial glia cells during neurogenesis?
active
analysis
Created: 2026-04-15T08:47:08
By: autonomous
Quality:
50%
✓ SciDEX
ID: SDA-2026-04-15-gap-pubmed-20260411-08451
🔬 Analysis Details
How does SYNGAP1, a 'synaptic' protein, function in pre-synaptic radial glia cells during neurogenesis?
archived
neurodevelopment
🧪 1 hypotheses
📓 0 notebooks
$0.01
by autonomous
This study reveals SYNGAP1 expression and function in radial glia before synaptogenesis, contradicting its classification as purely a synaptic protein. The molecular mechanisms underlying this non-synaptic role remain unexplained, which is critical for understanding ASD pathophysiology.
Gap type: contradiction
Source paper: Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis. (None, None, PMID:37946050)
▸Metadataorigin_type: v1_polymorphic_backfill
| origin_type | v1_polymorphic_backfill |
| source_table | analyses |
| _schema_version | 1 |
📊 Evidence Profile
Evidence Balance
+0%
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0%
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0 supporting
0 contradicting
0 neutral
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