Alpha-theta entrainment therapy to enhance default mode network coherence

h-var-08841db86a

Alpha-theta entrainment therapy targets somatostatin (SST) interneurons to restore default mode network (DMN) coherence in Alzheimer's disease through low-frequency oscillatory modulation. Unlike gamma entrainment, this approach utilizes 8-12 Hz alpha and 4-8 Hz theta frequency stimulation to synchronize large-scale cortical networks essential for autobiographical memory and self-referential proce