TREM2-Dependent Astrocyte-Microglia Cross-talk in Neuroinflammation

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TREM2-Dependent Astrocyte-Microglia Cross-talk in Neuroinflammation proposes that TREM2 dysfunction disrupts critical intercellular communication networks between microglia and astrocytes, leading to pathological neuroinflammation in neurodegenerative diseases. Under normal conditions, TREM2 signaling in microglia promotes the release of anti-inflammatory mediators including IL-10, TGF-β, and spec