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TREM2-Dependent Microglial Senescence Transition

h-61196ade
## Mechanistic Overview TREM2-Dependent Microglial Senescence Transition starts from the claim that modulating TREM2 within the disease context of neurodegeneration can redirect a disease-relevant process. The original description reads: "**Background and Rationale** Triggering Receptor Expressed on Myeloid cells 2 (TREM2) represents one of the most significant genetic risk factors for late-onset

Elo ratings (across arenas)

ArenaRatingRDW-L-DN
neurodegeneration 2088 ±68 55-16-0 71

Ancestry (oldest → this)

(no parents — root hypothesis)

Descendants