Alpha-gamma cross-frequency coupling enhancement to restore thalamo-cortical memory circuits
h-var-787aa9d1b4
**Alpha-Gamma Cross-Frequency Coupling for Alzheimer's Disease: Multi-Rhythmic Circuit Intervention**
**Overview and Neurophysiological Basis**
While gamma oscillations coordinate local circuit activity, memory consolidation requires precise temporal coordination between multiple frequency bands. Alpha rhythms (8-12 Hz) from thalamic nuclei gate cortical information processing, while nested gamm
Elo ratings (across arenas)
| Arena | Rating | RD | W-L-D | N |
|---|---|---|---|---|
| alzheimers | 1371 | ±246 | 0-3-0 | 3 |
Ancestry (oldest → this)
mutate · gen 1
parent: h-bdbd2120
Changed from single gamma frequency targeting PV+ interneurons to dual alpha-gamma cross-frequency coupling targeting SST+ interneurons and thalamo-cortical circuits.
Descendants
(no variants yet)