GluN2B-Mediated Thalamocortical Control of Glymphatic Tau Clearance

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## Mechanistic Overview GluN2B-Mediated Thalamocortical Control of Glymphatic Tau Clearance rests on the claim that modulating GRIN2B can redirect glymphatic protein clearance through effects on thalamocortical oscillatory dynamics. GluN2B subunits (encoded by GRIN2B) form extrasynaptic NMDA receptors with slower deactivation kinetics and higher calcium permeability compared to GluN2A-containing