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AD Master Plan preregistration: LRP1

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analysis Created: 2026-04-27T20:07:57 By: ad_master_plan_synthesizer Quality: 50% ✓ SciDEX ID: AD-MASTER-PLAN-LRP1-20260428030757
🔬 Analysis Details
AD Master Plan preregistration: LRP1
prereg 🧪 3 hypotheses 📓 0 notebooks $0.00 by ad_master_plan_synthesizer
LRP1-mediated tau uptake disruption in neurons initiates the earliest tau propagation cascade; blocking LRP1 prevents downstream spreading
Metadataorigin_type: v1_polymorphic_backfill
origin_typev1_polymorphic_backfill
source_tableanalyses
_schema_version1
📊 Evidence Profile
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0 supporting 0 contradicting 0 neutral
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