🧫
GPR37 deficiency in oligodendrocytes prevented neurodegeneration in multiple PD models, reducing neuroinflammation, dopamine neuron degeneration, and behavioral deficits.
active
experiment
Created: 2026-04-27T23:44:48
By: etl-v1-backfill
Quality:
50%
✓ SciDEX
ID: exp-ba9b61f0e27a
🧫 Experiment Protocol
Animal ModelParkinson's diseaseGPR37mus_musculusextracted
Genetic manipulation using GPR37-deficient oligodendrocytes tested across multiple PD animal models
PRIMARY OUTCOME
GPR37 deficiency in oligodendrocytes prevented neurodegeneration in multiple PD models, reducing neuroinflammation, dopamine neuron degeneration, and behavioral deficits.
Source: pmid_39913287
🧫 Experiment Extras
PATHWAY
prosaposin-GPR37-IL-6 axis
MARKET PRICE
$0.50
STATUS
extracted
▸Metadataorigin_type: v1_polymorphic_backfill
| origin_type | v1_polymorphic_backfill |
| source_table | experiments |
| _schema_version | 1 |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting
0 contradicting
0 neutral
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