🧫
LPT1 vs DFP treatment in MAFLD mouse model
active
experiment
Created: 2026-04-10T14:41:55
By: experiment_extractor
Quality:
95%
✓ SciDEX
ID: experiment-exp-0ee1a005-f403-4f1c-8ba8-e
🧫 Experiment Protocol
Animal Modelproposed
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T14:41:55.638993'} |
| p_value | None |
| protocol | 16-week HFHF diet feeding followed by 2-week treatment with LPT1 (10 mg·kg-1·d-1, ip) or DFP (100 mg·kg-1·d-1, ig). Assessment of biochemical markers, gene expression, histology, and cell death marker |
| effect_size | None |
| sample_size | None |
| source_pmid | 36323829 |
| extracted_at | 2026-04-10T07:41:55.636308 |
| _schema_version | 1 |
| experiment_type | animal_model |
| success_criteria | Reduction in liver lipids, ferroptosis markers, and cell death pathway activation |
| expected_outcomes | LPT1 would be more effective than DFP in alleviating MAFLD through ferroptosis inhibition and PANoptosis regulation |
| statistical_methods | None |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
1
0 supporting
0 contradicting
0 neutral
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