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Quantitative neuropathology characterization of 84 donors revealed stereotyped progression of proteinopathies with inflammatory changes in early disease and neuronal loss in late disease.

active
experiment Created: By: experiment_extractor Quality: 50% ✓ SciDEX ID: experiment-exp-256709628ab8
🧫 Experiment Protocol Neuropathologyproposed
SUMMARY
Quantitative neuropathology characterization of 84 donors revealed stereotyped progression of proteinopathies with inflammatory changes in early disease and neuronal loss in late disease.
METHODOLOGY NOTES
Neuropathology used to generate pseudoprogression score; cohort comprised 33 male and 51 female donors with average age 88 years at death
N = {'case': None, 'total': 84, 'units': 'subjects', 'control': None}tissue: middle temporal gyrusspecies: homo_sapiens
Metadatasource: {'pmid': '39402379', 'type': 'paper', 'e
source{'pmid': '39402379', 'type': 'paper', 'extracted_by': 'llm_extraction_v1'}
tissuemiddle temporal gyrus
specieshomo_sapiens
summaryQuantitative neuropathology characterization of 84 donors revealed stereotyped progression of proteinopathies with inflammatory changes in early disease and neuronal loss in late disease.
sample_size{'case': None, 'total': 84, 'units': 'subjects', 'control': None}
model_systemhuman
_schema_version1
experiment_typeneuropathology
methodology_notesNeuropathology used to generate pseudoprogression score; cohort comprised 33 male and 51 female donors with average age 88 years at death
replication_statusreplicated
extraction_metadata{'needs_review': False, 'extraction_date': '2026-04-28T06:14:42.345266+00:00', 'extraction_notes': '', 'extraction_confidence': 0.5}
statistical_evidenceNone
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